WORLD'S ONLY CONCENTRATION PREDICTOR

Stop Guessing Your Definitive Test Concentration Setting.

Designed specifically for beginners in ecotoxicology.

ToxGenie is the only software that automatically analyzes your range-finding data to predict an optimal geometric series for your definitive test, preventing costly experimental failures.

30-Day Free Trial • No Credit Card Required • Windows OS Only

100% AUTOMATED ANALYSIS FLOW

From Preliminary Data to Clear Visual Guidance

ToxGenie’s 3-step automated analysis flow for Definitive Test Concentration Setting:

Data input, smart pattern analysis, and visual projection.

STEP 1

Simple Data Input

Enter your limited range-finding survival or effect data into our standardized format.

STEP 2

Smart Pattern Analysis

The engine analyzes the rough dose-response pattern to calculate the optimal spacing and concentration bounds.

STEP 3

Output & Visual Projection

Instantly receive a recommended geometric concentration series alongside a Predictive Graph. This visual projection helps you understand how your definitive test curve might look before you even begin the experiment.

Tailored Predictions for Ecotoxicity Endpoints

ToxGenie optimizes your Definitive Test Concentration Setting by providing tailored predictive models for both acute and chronic endpoints.

Acute Toxicity Prediction

Acute tests require capturing the full dose-response curve. The algorithm recommends a geometric series spaced perfectly to capture the complete effect range from 0% to 100%, ensuring an accurate median lethal/effective concentration.

Chronic Toxicity Prediction

Chronic studies focus on sub-lethal, low-effect ranges. ToxGenie intelligently narrows and optimizes the concentration series to precisely detect the Threshold of No Observed Effect (NOEC) and Lowest Observed Effect Concentration (LOEC) values according to OECD chronic guidelines

Definitive Concentrations

Tailored Predictions for Ecotoxicity

ToxGenie optimizes your Definitive Test Concentration Setting by providing tailored predictive models for both acute and chronic endpoints.

Proven Accuracy and Reliability

ToxGenie yields results highly consistent with established methods, ensuring exceptional accuracy and reliability in its automated analysis.

Definitive Test Concentration Setting: Dose-response curve graphs and a table of predicted acute definitive test concentrations optimized by factors, generated by ToxGenie.

A Guide for Beginners, Not an Absolute Rule

While ToxGenie provides precise Definitive Test Concentration Setting,

it should be used as a strong reference guide alongside biological judgment.

Use these automated predictions to establish a solid foundation for your definitive test, but always apply your biological judgment and knowledge of the test species (e.g., Daphnia, Algae, Fish) to make the final decision.

What is a geometric concentration series, and why is it required?
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Toxicity doesn’t usually increase linearly; it increases logarithmically. OECD guidelines mandate a geometric series (e.g., multiplying each concentration by a constant factor like 2.0 or 3.2) to evenly space the data points along the logarithmic dose-response curve, preventing clustered or entirely missed effect ranges.

Currently, this prediction module is specifically optimized for ecotoxicology assays (e.g., aquatic organisms, algae). Mammalian in vivo testing often follows different stepping rules (like OECD 423 Acute Toxic Class method), which require specific fixed-dose procedures rather than purely calculated geometric series.

If no effects were observed, ToxGenie cannot mathematically predict a curve. In such cases, you likely need to perform a Limit Test at the highest required concentration (e.g., 100 mg/L) rather than a full definitive multi-dose test, as per OECD guideline

Generate Publication-Ready Statistical Reports.

ToxGenie eliminates the “Black Box.” Generate comprehensive statistical reports that include the exact rationale for model selection.

User-Selected Formats

Output your final report in either PDF (for secure, audit-ready archiving) or MS Word, depending on your current needs.

Manuscript & GLP Ready

Highly requested by our beta testers. Export to MS Word to seamlessly copy and paste the statistical rationale, tables, and graphs directly into your GLP Final Reports or academic papers.

Defensible Rationale

Every report explicitly justifies why a specific statistical method was applied, providing you with perfect defensibility for regulatory submissions (OECD, EPA).

Ready to automate your toxicology analysis?

Join the researchers and GLP contract research organizations saving hours on every study.

30-Day Free Trial • No Credit Card Required • Windows OS Only